Sevoflurane inhibits embryonic stem cell self-renewal and subsequent neural differentiation by modulating the let-7a-Lin28 signaling pathway.

Yi, Xiuwen

Sevoflurane inhibits embryonic stem cell self-renewal and subsequent neural differentiation by modulating the let-7a-Lin28 signaling pathway. [electronic resource] - Cell and tissue research 08 2016 - 319-30 p. digital

Publication Type: Journal Article

1432-0878

10.1007/s00441-016-2394-x doi


Anesthesia
Animals
Apoptosis--drug effects
Biomarkers--metabolism
Brain--drug effects
Cell Differentiation--drug effects
Cell Self Renewal--drug effects
Cell Survival--drug effects
Down-Regulation--drug effects
Embryonic Development--drug effects
Female
Gene Expression Regulation, Developmental--drug effects
Male
Methyl Ethers--pharmacology
Mice
Mice, Inbred C57BL
MicroRNAs--metabolism
Mouse Embryonic Stem Cells--cytology
Neurons--cytology
RNA-Binding Proteins--metabolism
Sevoflurane
Signal Transduction--drug effects
Up-Regulation--drug effects