Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1. [electronic resource]
Producer: 20171116Description: 761-74 p. digitalISSN:- 1942-0870
- AIDS Vaccines -- chemistry
- Animals
- Antibodies, Monoclonal -- chemistry
- Antibodies, Neutralizing -- chemistry
- Broadly Neutralizing Antibodies
- CD4 Antigens
- HIV-1 -- immunology
- Half-Life
- Humans
- Immunoglobulin Constant Regions -- chemistry
- Immunoglobulin Heavy Chains -- chemistry
- Immunoglobulin kappa-Chains -- chemistry
- Mice
- Mice, Inbred C57BL
- Protein Engineering -- methods
- Protein Stability
- Recombinant Fusion Proteins -- chemistry
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Publication Type: Journal Article
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