Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1.
Chen, Weizao
Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1. [electronic resource] - mAbs - 761-74 p. digital
Publication Type: Journal Article
1942-0870
10.1080/19420862.2016.1160180 doi
AIDS Vaccines--chemistry
Animals
Antibodies, Monoclonal--chemistry
Antibodies, Neutralizing--chemistry
Broadly Neutralizing Antibodies
CD4 Antigens
HIV-1--immunology
Half-Life
Humans
Immunoglobulin Constant Regions--chemistry
Immunoglobulin Heavy Chains--chemistry
Immunoglobulin kappa-Chains--chemistry
Mice
Mice, Inbred C57BL
Protein Engineering--methods
Protein Stability
Recombinant Fusion Proteins--chemistry
Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1. [electronic resource] - mAbs - 761-74 p. digital
Publication Type: Journal Article
1942-0870
10.1080/19420862.2016.1160180 doi
AIDS Vaccines--chemistry
Animals
Antibodies, Monoclonal--chemistry
Antibodies, Neutralizing--chemistry
Broadly Neutralizing Antibodies
CD4 Antigens
HIV-1--immunology
Half-Life
Humans
Immunoglobulin Constant Regions--chemistry
Immunoglobulin Heavy Chains--chemistry
Immunoglobulin kappa-Chains--chemistry
Mice
Mice, Inbred C57BL
Protein Engineering--methods
Protein Stability
Recombinant Fusion Proteins--chemistry