Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma. [electronic resource]
Producer: 20170629Description: 1043-52 p. digitalISSN:- 1538-8514
- Adenocarcinoma -- drug therapy
- Adult
- Aged
- Aged, 80 and over
- Animals
- Antineoplastic Agents -- pharmacology
- Carcinoma, Pancreatic Ductal -- drug therapy
- Cell Line, Tumor
- Deoxycytidine -- analogs & derivatives
- Disease Models, Animal
- Drug Resistance, Neoplasm -- genetics
- Drug Synergism
- Endoplasmic Reticulum Chaperone BiP
- Endoplasmic Reticulum Stress -- genetics
- Female
- Gene Expression
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Knockdown Techniques
- Heat-Shock Proteins -- genetics
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Proto-Oncogene Proteins c-akt -- genetics
- Survival Analysis
- Unfolded Protein Response
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Journal Article
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