Comparative effects of azapropazone on cellular events at inflamed sites. Influence on joint pathology in arthritic rats, leucocyte superoxide and eicosanoid production, platelet aggregation, synthesis of cartilage proteoglycans, synovial production and actions of interleukin-1 in cartilage resorption correlated with drug uptake into cartilage in-vitro. [electronic resource]
Producer: 19890921Description: 322-30 p. digitalISSN:- 0022-3573
- Animals
- Apazone -- pharmacokinetics
- Arthritis -- physiopathology
- Arthritis, Experimental -- metabolism
- Cartilage, Articular -- metabolism
- Cattle
- Female
- In Vitro Techniques
- Interleukin-1 -- metabolism
- Leukocytes -- metabolism
- Neutrophils -- drug effects
- Platelet Aggregation -- drug effects
- Prostaglandins -- biosynthesis
- Proteoglycans -- metabolism
- Rats
- Rats, Inbred Strains
- Superoxides
- Swine
- Synovial Membrane -- drug effects
- Triazines -- pharmacology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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