iRGD-targeted delivery of a pro-apoptotic peptide activated by cathepsin B inhibits tumor growth and metastasis in mice. [electronic resource]
Producer: 20170221Description: 10643-52 p. digitalISSN:- 1423-0380
- Activation, Metabolic
- Amino Acid Sequence
- Animals
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- drug effects
- Breast Neoplasms -- pathology
- Cathepsin B -- metabolism
- Cell Division -- drug effects
- Cell Line, Tumor
- Cell-Penetrating Peptides -- administration & dosage
- Drug Carriers -- administration & dosage
- Drug Screening Assays, Antitumor
- Female
- Humans
- Mammary Neoplasms, Experimental -- drug therapy
- Melanoma, Experimental -- pathology
- Mice
- Mice, Inbred BALB C
- Mitochondria -- drug effects
- Neoplasm Metastasis
- Neuropilin-1 -- physiology
- Oligopeptides -- administration & dosage
- Prodrugs -- administration & dosage
- fas Receptor -- physiology
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Publication Type: Journal Article
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