Pharmacologically induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset. [electronic resource]
Producer: 20161213Description: 964-75 p. digitalISSN:- 1460-2083
- Adolescent
- Adult
- Age of Onset
- Animals
- Dependovirus -- genetics
- Disease Models, Animal
- Follistatin -- pharmacology
- Gene Deletion
- Genetic Vectors -- chemistry
- Humans
- Immunologic Factors -- pharmacology
- Mice
- Motor Neurons -- drug effects
- Muscular Atrophy, Spinal -- drug therapy
- Myostatin -- antagonists & inhibitors
- Phenotype
- RNA Splicing -- drug effects
- Survival of Motor Neuron 1 Protein -- genetics
- Survival of Motor Neuron 2 Protein -- agonists
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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