Torin2 Potentiates Anticancer Effects on Adult T-Cell Leukemia/Lymphoma by Inhibiting Mammalian Target of Rapamycin. [electronic resource]
Producer: 20160503Description: 95-102 p. digitalISSN:- 1791-7530
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Etoposide -- pharmacology
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Leukemia-Lymphoma, Adult T-Cell -- drug therapy
- Mechanistic Target of Rapamycin Complex 1
- Mechanistic Target of Rapamycin Complex 2
- Multiprotein Complexes -- antagonists & inhibitors
- Naphthyridines -- pharmacology
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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