Torin2 Potentiates Anticancer Effects on Adult T-Cell Leukemia/Lymphoma by Inhibiting Mammalian Target of Rapamycin.

Watanabe, Tatsuro

Torin2 Potentiates Anticancer Effects on Adult T-Cell Leukemia/Lymphoma by Inhibiting Mammalian Target of Rapamycin. [electronic resource] - Anticancer research Jan 2016 - 95-102 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1791-7530


Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Dose-Response Relationship, Drug
Etoposide--pharmacology
G1 Phase Cell Cycle Checkpoints--drug effects
Humans
Leukemia-Lymphoma, Adult T-Cell--drug therapy
Mechanistic Target of Rapamycin Complex 1
Mechanistic Target of Rapamycin Complex 2
Multiprotein Complexes--antagonists & inhibitors
Naphthyridines--pharmacology
Phosphorylation
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
Sirolimus--pharmacology
TOR Serine-Threonine Kinases--antagonists & inhibitors