HDAC inhibition impedes epithelial-mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer. [electronic resource]
Producer: 20170911Description: 3781-95 p. digitalISSN:- 1476-5594
- Animals
- Blotting, Western
- Cell Line, Tumor
- Disease Models, Animal
- Epithelial-Mesenchymal Transition -- drug effects
- Gene Expression Profiling -- methods
- Gene Expression Regulation, Neoplastic -- drug effects
- Histone Deacetylase Inhibitors -- pharmacology
- Humans
- Hydroxamic Acids -- pharmacology
- Indoles -- pharmacology
- Male
- Mice, Inbred NOD
- Mice, Knockout
- Mice, SCID
- Mice, Transgenic
- Mitogen-Activated Protein Kinases -- metabolism
- Neoplasm Metastasis
- PTEN Phosphohydrolase -- genetics
- Panobinostat
- Phosphatidylinositol 3-Kinases -- metabolism
- Prostatic Neoplasms, Castration-Resistant -- drug therapy
- Proto-Oncogene Proteins c-akt -- metabolism
- Proto-Oncogene Proteins p21(ras) -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
No physical items for this record
Publication Type: Journal Article
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