Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents. [electronic resource]
Producer: 20160920Description: 219-32 p. digitalISSN:- 1768-3254
- Acetylcholinesterase -- chemistry
- Alzheimer Disease -- drug therapy
- Animals
- Antioxidants -- chemistry
- Binding Sites
- Butyrylcholinesterase -- metabolism
- Chemistry Techniques, Synthetic
- Cholinesterase Inhibitors -- chemistry
- Computer Simulation
- Coumarins -- chemical synthesis
- Drug Evaluation, Preclinical -- methods
- Galantamine -- pharmacology
- Humans
- Hydrogen Peroxide -- toxicity
- Male
- Mice, Inbred BALB C
- Models, Molecular
- Neuroprotective Agents -- chemical synthesis
- Neurotoxicity Syndromes -- etiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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