Insights into the molecular interactions of thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer. [electronic resource]
Producer: 20160915Description: 48-58 p. digitalISSN:- 1742-2051
- Amino Acid Sequence
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- genetics
- Benzoquinones -- chemistry
- Breast Neoplasms -- drug therapy
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- DNA Damage -- drug effects
- Enzyme Activation -- drug effects
- Female
- Gene Expression
- Histone Deacetylase Inhibitors -- chemistry
- Histone Deacetylases -- chemistry
- Humans
- Hydrogen Bonding
- Models, Molecular
- Molecular Conformation
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- Molecular Sequence Data
- Protein Binding
- Sequence Alignment
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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