Insights into the molecular interactions of thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer.
Parbin, Sabnam
Insights into the molecular interactions of thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer. [electronic resource] - Molecular bioSystems Jan 2016 - 48-58 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1742-2051
10.1039/c5mb00412h doi
Amino Acid Sequence
Apoptosis--drug effects
Apoptosis Regulatory Proteins--genetics
Benzoquinones--chemistry
Breast Neoplasms--drug therapy
Cell Cycle--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
DNA Damage--drug effects
Enzyme Activation--drug effects
Female
Gene Expression
Histone Deacetylase Inhibitors--chemistry
Histone Deacetylases--chemistry
Humans
Hydrogen Bonding
Models, Molecular
Molecular Conformation
Molecular Docking Simulation
Molecular Dynamics Simulation
Molecular Sequence Data
Protein Binding
Sequence Alignment
Structure-Activity Relationship
Insights into the molecular interactions of thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer. [electronic resource] - Molecular bioSystems Jan 2016 - 48-58 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1742-2051
10.1039/c5mb00412h doi
Amino Acid Sequence
Apoptosis--drug effects
Apoptosis Regulatory Proteins--genetics
Benzoquinones--chemistry
Breast Neoplasms--drug therapy
Cell Cycle--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
DNA Damage--drug effects
Enzyme Activation--drug effects
Female
Gene Expression
Histone Deacetylase Inhibitors--chemistry
Histone Deacetylases--chemistry
Humans
Hydrogen Bonding
Models, Molecular
Molecular Conformation
Molecular Docking Simulation
Molecular Dynamics Simulation
Molecular Sequence Data
Protein Binding
Sequence Alignment
Structure-Activity Relationship