Inactivation of TGFβ receptor II signalling in pancreatic epithelial cells promotes acinar cell proliferation, acinar-to-ductal metaplasia and fibrosis during pancreatitis. [electronic resource]
Producer: 20160524Description: 434-45 p. digitalISSN:- 1096-9896
- Acinar Cells -- pathology
- Amylases -- metabolism
- Animals
- Carcinoma, Pancreatic Ductal -- pathology
- Cell Cycle Checkpoints -- physiology
- Cell Proliferation -- physiology
- Cell Transformation, Neoplastic -- pathology
- Cells, Cultured
- Ceruletide -- toxicity
- Epithelial Cells -- pathology
- Fibrosis -- pathology
- Irritants -- toxicity
- Lipase -- metabolism
- Male
- Metaplasia -- pathology
- Mice, Knockout
- Mice, Transgenic
- Pancreas -- enzymology
- Pancreatic Neoplasms -- pathology
- Pancreatitis -- enzymology
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Transforming Growth Factor beta -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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