The Hedgehog pathway as targetable vulnerability with 5-azacytidine in myelodysplastic syndrome and acute myeloid leukemia. [electronic resource]
Producer: 20160711Description: 114 p. digitalISSN:- 1756-8722
- Acute Disease
- Aged
- Aged, 80 and over
- Anilides -- pharmacology
- Antimetabolites, Antineoplastic -- pharmacology
- Azacitidine -- pharmacology
- Biphenyl Compounds -- pharmacology
- Cell Line, Tumor
- Cell Survival -- drug effects
- Chromosomes, Human, Pair 5 -- genetics
- Chromosomes, Human, Pair 7 -- genetics
- Drug Synergism
- Female
- HL-60 Cells
- Hedgehog Proteins -- genetics
- High-Throughput Nucleotide Sequencing -- methods
- Humans
- Leukemia, Myeloid -- drug therapy
- Male
- Myelodysplastic Syndromes -- drug therapy
- Pyridines -- pharmacology
- RNA Interference
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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