The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation. [electronic resource]
Producer: 20160412Description: 1263-73 p. digitalISSN:- 1529-2916
- Animals
- Cell Differentiation -- immunology
- Cells, Cultured
- Colitis -- chemically induced
- Colitis, Ulcerative -- genetics
- Cytokines -- immunology
- DNA Methylation -- immunology
- Dextran Sulfate
- Dual Specificity Phosphatase 2 -- deficiency
- Gene Expression Regulation -- immunology
- HEK293 Cells
- Humans
- Immunoblotting
- Inflammation Mediators -- immunology
- Mice, Inbred C57BL
- Mice, Knockout
- Phosphorylation -- immunology
- Protein Binding -- immunology
- Reverse Transcriptase Polymerase Chain Reaction
- STAT3 Transcription Factor -- immunology
- Th17 Cells -- immunology
- Tyrosine -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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