Myeloperoxidase-derived hypochlorous acid promotes ox-LDL-induced senescence of endothelial cells through a mechanism involving β-catenin signaling in hyperlipidemia. [electronic resource]
Producer: 20160503Description: 859-65 p. digitalISSN:- 1090-2104
- Animals
- Cellular Senescence
- Endothelial Cells -- drug effects
- Endothelium, Vascular -- metabolism
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Human Umbilical Vein Endothelial Cells -- drug effects
- Hyperlipidemias -- metabolism
- Hypochlorous Acid -- metabolism
- Lipids -- blood
- Lipoproteins, LDL -- metabolism
- Male
- Peroxidase -- chemistry
- Rats, Sprague-Dawley
- Tumor Suppressor Protein p53 -- metabolism
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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