Myeloperoxidase-derived hypochlorous acid promotes ox-LDL-induced senescence of endothelial cells through a mechanism involving β-catenin signaling in hyperlipidemia.
Liu, Wei-Qi
Myeloperoxidase-derived hypochlorous acid promotes ox-LDL-induced senescence of endothelial cells through a mechanism involving β-catenin signaling in hyperlipidemia. [electronic resource] - Biochemical and biophysical research communications Nov 2015 - 859-65 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1090-2104
10.1016/j.bbrc.2015.10.053 doi
Animals
Cellular Senescence
Endothelial Cells--drug effects
Endothelium, Vascular--metabolism
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Human Umbilical Vein Endothelial Cells--drug effects
Hyperlipidemias--metabolism
Hypochlorous Acid--metabolism
Lipids--blood
Lipoproteins, LDL--metabolism
Male
Peroxidase--chemistry
Rats, Sprague-Dawley
Tumor Suppressor Protein p53--metabolism
beta Catenin--metabolism
Myeloperoxidase-derived hypochlorous acid promotes ox-LDL-induced senescence of endothelial cells through a mechanism involving β-catenin signaling in hyperlipidemia. [electronic resource] - Biochemical and biophysical research communications Nov 2015 - 859-65 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1090-2104
10.1016/j.bbrc.2015.10.053 doi
Animals
Cellular Senescence
Endothelial Cells--drug effects
Endothelium, Vascular--metabolism
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Human Umbilical Vein Endothelial Cells--drug effects
Hyperlipidemias--metabolism
Hypochlorous Acid--metabolism
Lipids--blood
Lipoproteins, LDL--metabolism
Male
Peroxidase--chemistry
Rats, Sprague-Dawley
Tumor Suppressor Protein p53--metabolism
beta Catenin--metabolism