Novel phase I study combining G1 phase, S phase, and G2/M phase cell cycle inhibitors in patients with advanced malignancies. [electronic resource]
Producer: 20160829Description: 3434-40 p. digitalISSN:- 1551-4005
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antineoplastic Combined Chemotherapy Protocols -- adverse effects
- Bortezomib -- administration & dosage
- Computer Simulation
- Disease Progression
- Disease-Free Survival
- Drug Administration Schedule
- Female
- G1 Phase Cell Cycle Checkpoints -- drug effects
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Kaplan-Meier Estimate
- Male
- Maximum Tolerated Dose
- Middle Aged
- Models, Biological
- Molecular Targeted Therapy
- Neoplasms -- drug therapy
- S Phase Cell Cycle Checkpoints -- drug effects
- Sirolimus -- administration & dosage
- Texas
- Time Factors
- Topotecan -- administration & dosage
- Treatment Outcome
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article
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