Novel phase I study combining G1 phase, S phase, and G2/M phase cell cycle inhibitors in patients with advanced malignancies.

Jain, Rajul K

Novel phase I study combining G1 phase, S phase, and G2/M phase cell cycle inhibitors in patients with advanced malignancies. [electronic resource] - Cell cycle (Georgetown, Tex.) 2015 - 3434-40 p. digital

Publication Type: Clinical Trial, Phase I; Journal Article

1551-4005

10.1080/15384101.2015.1090065 doi


Adolescent
Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols--adverse effects
Bortezomib--administration & dosage
Computer Simulation
Disease Progression
Disease-Free Survival
Drug Administration Schedule
Female
G1 Phase Cell Cycle Checkpoints--drug effects
G2 Phase Cell Cycle Checkpoints--drug effects
Humans
Kaplan-Meier Estimate
Male
Maximum Tolerated Dose
Middle Aged
Models, Biological
Molecular Targeted Therapy
Neoplasms--drug therapy
S Phase Cell Cycle Checkpoints--drug effects
Sirolimus--administration & dosage
Texas
Time Factors
Topotecan--administration & dosage
Treatment Outcome
Young Adult