Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease. [electronic resource]
Producer: 20170327Description: 1264-9 p. digitalISSN:- 1860-7187
- Acetylcholinesterase -- chemistry
- Alzheimer Disease -- drug therapy
- Blood-Brain Barrier -- metabolism
- Cell Survival -- drug effects
- Cholinesterase Inhibitors -- chemical synthesis
- Drug Design
- Hep G2 Cells
- Humans
- Indoles -- chemical synthesis
- Inhibitory Concentration 50
- Ligands
- Monoamine Oxidase -- chemistry
- Monoamine Oxidase Inhibitors -- chemical synthesis
- Quinolines -- chemical synthesis
- Structure-Activity Relationship
- Tacrine -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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