LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner. [electronic resource]
Producer: 20160603Description: 582-94 p. digitalISSN:- 1362-4962
- Binding Sites
- Cell Proliferation -- genetics
- Chromatin Assembly and Disassembly
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Gene Deletion
- Gene Expression Regulation, Neoplastic
- HCT116 Cells
- HT29 Cells
- Humans
- Mutation
- Organ Specificity
- Phosphorylation
- Promoter Regions, Genetic
- Protein Binding
- RNA, Small Interfering -- genetics
- Receptors, Cytoplasmic and Nuclear -- genetics
- Signal Transduction
- Tumor Suppressor Protein p53 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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