LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner.
Kramer, Holly B
LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner. [electronic resource] - Nucleic acids research Jan 2016 - 582-94 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1362-4962
10.1093/nar/gkv948 doi
Binding Sites
Cell Proliferation--genetics
Chromatin Assembly and Disassembly
Cyclin-Dependent Kinase Inhibitor p21--genetics
Gene Deletion
Gene Expression Regulation, Neoplastic
HCT116 Cells
HT29 Cells
Humans
Mutation
Organ Specificity
Phosphorylation
Promoter Regions, Genetic
Protein Binding
RNA, Small Interfering--genetics
Receptors, Cytoplasmic and Nuclear--genetics
Signal Transduction
Tumor Suppressor Protein p53--antagonists & inhibitors
LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner. [electronic resource] - Nucleic acids research Jan 2016 - 582-94 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1362-4962
10.1093/nar/gkv948 doi
Binding Sites
Cell Proliferation--genetics
Chromatin Assembly and Disassembly
Cyclin-Dependent Kinase Inhibitor p21--genetics
Gene Deletion
Gene Expression Regulation, Neoplastic
HCT116 Cells
HT29 Cells
Humans
Mutation
Organ Specificity
Phosphorylation
Promoter Regions, Genetic
Protein Binding
RNA, Small Interfering--genetics
Receptors, Cytoplasmic and Nuclear--genetics
Signal Transduction
Tumor Suppressor Protein p53--antagonists & inhibitors