PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs. [electronic resource]
Producer: 20160706Description: 1978-85 p. digitalISSN:- 2211-1247
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Colonic Neoplasms -- drug therapy
- Drug Resistance, Neoplasm -- drug effects
- ErbB Receptors -- genetics
- Gene Expression Regulation, Neoplastic
- Genetic Vectors
- Genomic Library
- High-Throughput Nucleotide Sequencing
- Humans
- Indoles -- pharmacology
- Lentivirus -- genetics
- MAP Kinase Signaling System
- Melanoma -- drug therapy
- Mice
- Mice, Inbred NOD
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 -- antagonists & inhibitors
- Proto-Oncogene Proteins B-raf -- genetics
- RNA, Small Interfering -- genetics
- Sulfonamides -- pharmacology
- Transduction, Genetic
- Vemurafenib
- Xenograft Model Antitumor Assays
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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