Characterizing the Diverse Mutational Pathways Associated with R5-Tropic Maraviroc Resistance: HIV-1 That Uses the Drug-Bound CCR5 Coreceptor. [electronic resource]
Producer: 20160129Description: 11457-72 p. digitalISSN:- 1098-5514
- Amino Acid Sequence
- Base Sequence
- CCR5 Receptor Antagonists -- therapeutic use
- Clinical Trials as Topic
- Cyclohexanes -- therapeutic use
- Drug Resistance, Viral -- genetics
- Glycosylation
- HIV Envelope Protein gp120 -- genetics
- HIV Envelope Protein gp41 -- genetics
- HIV Fusion Inhibitors -- therapeutic use
- HIV Infections -- drug therapy
- HIV-1 -- drug effects
- Humans
- Maraviroc
- Molecular Sequence Data
- Protein Structure, Tertiary
- Receptors, CCR5 -- metabolism
- Receptors, CXCR4 -- metabolism
- Sequence Alignment
- Sequence Analysis, RNA
- Signal Transduction -- genetics
- Treatment Failure
- Triazoles -- therapeutic use
- Virus Internalization -- drug effects
- Virus Replication -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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