Nuclear EGFR renders cells radio-resistant by binding mRNA species and triggering a metabolic switch to increase lactate production. [electronic resource]
Producer: 20160601Description: 431-7 p. digitalISSN:- 1879-0887
- Blotting, Western
- Bronchial Neoplasms -- metabolism
- Cell Line, Tumor
- Cell Nucleus -- metabolism
- Dasatinib -- pharmacology
- ErbB Receptors -- antagonists & inhibitors
- Erlotinib Hydrochloride -- pharmacology
- Gene Expression
- Head and Neck Neoplasms -- metabolism
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- Lactic Acid -- biosynthesis
- Nuclear Proteins -- metabolism
- Oxadiazoles -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Pyrazoles -- pharmacology
- RNA, Messenger -- metabolism
- Radiation Tolerance -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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