Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux. [electronic resource]
Producer: 20160913Description: 1891-904 p. digitalISSN:- 1554-8635
- Angiogenesis Inhibitors -- pharmacology
- Autophagy -- drug effects
- Carcinoma, Renal Cell -- drug therapy
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- Humans
- Indoles -- pharmacology
- Lysosomes -- drug effects
- Neoplasm Recurrence, Local -- metabolism
- Neovascularization, Pathologic -- drug therapy
- Pyrroles -- pharmacology
- Sunitinib
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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