Impact of inhalational exposure to ethanol fuel on the pharmacokinetics of verapamil, ibuprofen and fluoxetine as in vivo probe drugs for CYP3A, CYP2C and CYP2D in rats. [electronic resource]
Producer: 20160801Description: 99-105 p. digitalISSN:- 1873-6351
- Air Pollutants, Occupational -- toxicity
- Animals
- Aryl Hydrocarbon Hydroxylases -- antagonists & inhibitors
- Atmosphere Exposure Chambers
- Biofuels -- toxicity
- Biomarkers -- blood
- Biotransformation -- drug effects
- Cytochrome P-450 CYP3A -- chemistry
- Cytochrome P-450 Enzyme Inducers -- toxicity
- Cytochrome P-450 Enzyme Inhibitors -- blood
- Cytochrome P-450 Enzyme System -- chemistry
- Enzyme Induction -- drug effects
- Ethanol -- toxicity
- Fluoxetine -- blood
- Ibuprofen -- blood
- Inhalation Exposure -- adverse effects
- Limonene Hydroxylases -- antagonists & inhibitors
- Male
- Rats, Wistar
- Toxicity Tests, Chronic -- methods
- Verapamil -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Study
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