Tanshinone IIA represses inflammatory response and reduces radiculopathic pain by inhibiting IRAK-1 and NF-κB/p38/JNK signaling. [electronic resource]
Producer: 20160629Description: 382-9 p. digitalISSN:- 1878-1705
- Abietanes -- pharmacology
- Analgesics -- pharmacology
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Cell Survival -- drug effects
- Cells, Cultured
- Cyclooxygenase 2 -- genetics
- Drugs, Chinese Herbal -- pharmacology
- Female
- Humans
- Interleukin-1 Receptor-Associated Kinases -- metabolism
- Interleukin-1beta
- Intervertebral Disc -- cytology
- Intervertebral Disc Degeneration -- drug therapy
- Intervertebral Disc Displacement -- drug therapy
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Matrix Metalloproteinase 1 -- genetics
- Matrix Metalloproteinase 13 -- genetics
- NF-kappa B -- metabolism
- Nitric Oxide Synthase Type II -- genetics
- Pain -- drug therapy
- Rats, Sprague-Dawley
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article
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