The -308 TNFα and the -174 IL-6 promoter polymorphisms associate with effective anti-TNFα treatment in seronegative spondyloarthritis. [electronic resource]
Producer: 20170309Description: 238-42 p. digitalISSN:- 1473-1150
- Adult
- Aged
- Aged, 80 and over
- Antirheumatic Agents -- adverse effects
- Biological Products -- adverse effects
- Chi-Square Distribution
- Drug Substitution
- Female
- Genetic Association Studies
- Homozygote
- Humans
- Interleukin-6 -- genetics
- Italy
- Logistic Models
- Male
- Middle Aged
- Multivariate Analysis
- Odds Ratio
- Pharmacogenomic Testing
- Pharmacogenomic Variants -- genetics
- Phenotype
- Polymorphism, Single Nucleotide
- Predictive Value of Tests
- Promoter Regions, Genetic
- Retrospective Studies
- Risk Assessment
- Risk Factors
- Sex Factors
- Spondylarthritis -- blood
- Time Factors
- Treatment Failure
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- Young Adult
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Publication Type: Journal Article; Multicenter Study
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