Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates. [electronic resource]
Producer: 20151014Description: 285-97 p. digitalISSN:- 1097-4164
- Amino Acid Sequence
- Animals
- Autophagy -- drug effects
- Autophagy-Related Protein-1 Homolog
- Benzamides -- chemistry
- Catalytic Domain -- genetics
- Cell Survival -- drug effects
- Cells, Cultured
- Consensus Sequence
- Gene Knockout Techniques
- HEK293 Cells
- Humans
- Intracellular Signaling Peptides and Proteins -- antagonists & inhibitors
- Mice
- Molecular Sequence Data
- Phosphorylation
- Protein Kinase Inhibitors -- chemistry
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Pyrimidines -- chemistry
- RNA, Small Interfering -- genetics
- Recombinant Proteins -- chemistry
- Substrate Specificity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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