Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.

Egan, Daniel F

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates. [electronic resource] - Molecular cell Jul 2015 - 285-97 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1097-4164

10.1016/j.molcel.2015.05.031 doi


Amino Acid Sequence
Animals
Autophagy--drug effects
Autophagy-Related Protein-1 Homolog
Benzamides--chemistry
Catalytic Domain--genetics
Cell Survival--drug effects
Cells, Cultured
Consensus Sequence
Gene Knockout Techniques
HEK293 Cells
Humans
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Mice
Molecular Sequence Data
Phosphorylation
Protein Kinase Inhibitors--chemistry
Protein Serine-Threonine Kinases--antagonists & inhibitors
Pyrimidines--chemistry
RNA, Small Interfering--genetics
Recombinant Proteins--chemistry
Substrate Specificity