Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy. [electronic resource]
Producer: 20160422Description: 89-100 p. digitalISSN:- 1875-9777
- Adrenergic beta-Agonists -- pharmacology
- Cardiomyopathy, Dilated -- genetics
- Cell Differentiation
- Cells, Cultured
- Cyclic Nucleotide Phosphodiesterases, Type 2 -- genetics
- Cyclic Nucleotide Phosphodiesterases, Type 3 -- genetics
- Epigenesis, Genetic
- Heart Rate -- drug effects
- Humans
- Induced Pluripotent Stem Cells -- drug effects
- Isoproterenol -- pharmacology
- Models, Cardiovascular
- Mutant Proteins -- genetics
- Mutation
- Myocardial Contraction -- drug effects
- Myocytes, Cardiac -- drug effects
- Receptors, Adrenergic, beta -- metabolism
- Signal Transduction
- Troponin T -- genetics
- Up-Regulation
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.