TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response. [electronic resource]
Producer: 20160304Description: e0129566 p. digitalISSN:- 1932-6203
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Dose-Response Relationship, Drug
- Doxorubicin -- pharmacology
- Drug Discovery
- Glutathione -- metabolism
- Glutathione Reductase -- antagonists & inhibitors
- High-Throughput Screening Assays
- Humans
- Mice
- Oxidative Stress
- Reactive Oxygen Species
- Small Molecule Libraries
- TNF-Related Apoptosis-Inducing Ligand -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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