Sequence Analysis of Herpes Simplex Virus 1 Thymidine Kinase and DNA Polymerase Genes from over 300 Clinical Isolates from 1973 to 2014 Finds Novel Mutations That May Be Relevant for Development of Antiviral Resistance. [electronic resource]
Producer: 20160414Description: 4938-45 p. digitalISSN:- 1098-6596
- Acyclovir -- therapeutic use
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antiviral Agents -- therapeutic use
- Child
- Child, Preschool
- DNA-Directed DNA Polymerase -- genetics
- Drug Resistance, Viral -- genetics
- Female
- Foscarnet -- therapeutic use
- Genotype
- Herpes Simplex -- drug therapy
- Herpesvirus 1, Human -- drug effects
- Humans
- Infant
- Infant, Newborn
- Male
- Middle Aged
- Mutation -- genetics
- Polymorphism, Genetic -- genetics
- Retrospective Studies
- Sequence Analysis, DNA -- methods
- Thymidine Kinase -- genetics
- Viral Proteins -- genetics
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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