Sequence Analysis of Herpes Simplex Virus 1 Thymidine Kinase and DNA Polymerase Genes from over 300 Clinical Isolates from 1973 to 2014 Finds Novel Mutations That May Be Relevant for Development of Antiviral Resistance.

Schmidt, Susanne

Sequence Analysis of Herpes Simplex Virus 1 Thymidine Kinase and DNA Polymerase Genes from over 300 Clinical Isolates from 1973 to 2014 Finds Novel Mutations That May Be Relevant for Development of Antiviral Resistance. [electronic resource] - Antimicrobial agents and chemotherapy Aug 2015 - 4938-45 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1098-6596

10.1128/AAC.00977-15 doi


Acyclovir--therapeutic use
Adolescent
Adult
Aged
Aged, 80 and over
Antiviral Agents--therapeutic use
Child
Child, Preschool
DNA-Directed DNA Polymerase--genetics
Drug Resistance, Viral--genetics
Female
Foscarnet--therapeutic use
Genotype
Herpes Simplex--drug therapy
Herpesvirus 1, Human--drug effects
Humans
Infant
Infant, Newborn
Male
Middle Aged
Mutation--genetics
Polymorphism, Genetic--genetics
Retrospective Studies
Sequence Analysis, DNA--methods
Thymidine Kinase--genetics
Viral Proteins--genetics
Young Adult