Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib. [electronic resource]
Producer: 20160610Description: 21636-44 p. digitalISSN:- 1949-2553
- Aged
- Aged, 80 and over
- Antineoplastic Agents -- therapeutic use
- Biomarkers -- metabolism
- Biomarkers, Tumor -- metabolism
- Biopsy, Fine-Needle
- Carcinoma, Hepatocellular -- drug therapy
- Female
- Formaldehyde -- chemistry
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- High-Throughput Nucleotide Sequencing -- methods
- Humans
- Liver Neoplasms -- drug therapy
- Male
- Middle Aged
- Mutation
- Neuregulin-1 -- genetics
- Niacinamide -- analogs & derivatives
- Paraffin Embedding
- Phenylurea Compounds -- therapeutic use
- Platelet Endothelial Cell Adhesion Molecule-1 -- genetics
- Sequence Analysis, DNA
- Sequence Analysis, RNA
- Sorafenib
- Transforming Growth Factor alpha -- genetics
- Treatment Outcome
- Tumor Suppressor Protein p53 -- genetics
- beta Catenin -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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