Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib.

Sakai, Kazuko

Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib. [electronic resource] - Oncotarget Aug 2015 - 21636-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.4270 doi


Aged
Aged, 80 and over
Antineoplastic Agents--therapeutic use
Biomarkers--metabolism
Biomarkers, Tumor--metabolism
Biopsy, Fine-Needle
Carcinoma, Hepatocellular--drug therapy
Female
Formaldehyde--chemistry
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
High-Throughput Nucleotide Sequencing--methods
Humans
Liver Neoplasms--drug therapy
Male
Middle Aged
Mutation
Neuregulin-1--genetics
Niacinamide--analogs & derivatives
Paraffin Embedding
Phenylurea Compounds--therapeutic use
Platelet Endothelial Cell Adhesion Molecule-1--genetics
Sequence Analysis, DNA
Sequence Analysis, RNA
Sorafenib
Transforming Growth Factor alpha--genetics
Treatment Outcome
Tumor Suppressor Protein p53--genetics
beta Catenin--genetics