Human chromosome segregation involves multi-layered regulation of separase by the peptidyl-prolyl-isomerase Pin1. [electronic resource]
Producer: 20150731Description: 495-506 p. digitalISSN:- 1097-4164
- Anaphase -- genetics
- CDC2 Protein Kinase
- Chromatids -- genetics
- Chromosome Segregation -- genetics
- Cyclin B1 -- chemistry
- Cyclin-Dependent Kinases -- chemistry
- Gene Expression Regulation, Enzymologic
- HEK293 Cells
- Humans
- Immunoblotting
- Metaphase -- genetics
- Microscopy, Fluorescence
- Mitosis -- genetics
- Models, Genetic
- Models, Molecular
- Mutation
- NIMA-Interacting Peptidylprolyl Isomerase
- Peptidylprolyl Isomerase -- genetics
- Protein Binding
- Protein Conformation
- RNA Interference
- Securin -- genetics
- Separase -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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