Human chromosome segregation involves multi-layered regulation of separase by the peptidyl-prolyl-isomerase Pin1.

Hellmuth, Susanne

Human chromosome segregation involves multi-layered regulation of separase by the peptidyl-prolyl-isomerase Pin1. [electronic resource] - Molecular cell May 2015 - 495-506 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-4164

10.1016/j.molcel.2015.03.025 doi


Anaphase--genetics
CDC2 Protein Kinase
Chromatids--genetics
Chromosome Segregation--genetics
Cyclin B1--chemistry
Cyclin-Dependent Kinases--chemistry
Gene Expression Regulation, Enzymologic
HEK293 Cells
Humans
Immunoblotting
Metaphase--genetics
Microscopy, Fluorescence
Mitosis--genetics
Models, Genetic
Models, Molecular
Mutation
NIMA-Interacting Peptidylprolyl Isomerase
Peptidylprolyl Isomerase--genetics
Protein Binding
Protein Conformation
RNA Interference
Securin--genetics
Separase--chemistry