Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease. [electronic resource]
Producer: 20150826Description: 17-28 p. digitalISSN:- 1524-4571
- ATP Binding Cassette Transporter 1 -- deficiency
- Adult
- Aged
- Animals
- Antigens, Differentiation -- analysis
- Base Sequence
- Cell Culture Techniques
- Cell Differentiation
- Cells, Cultured
- Cholesterol -- metabolism
- Embryoid Bodies -- cytology
- Female
- Genotype
- Humans
- Induced Pluripotent Stem Cells -- cytology
- Inflammation
- Interferon-gamma -- pharmacology
- Lipopolysaccharides -- pharmacology
- Macrophage Activation -- drug effects
- Macrophages -- cytology
- Male
- Mice
- Mice, Knockout
- Molecular Sequence Data
- Phagocytosis
- Phenotype
- RNA, Messenger -- genetics
- Sequence Alignment
- Sequence Homology, Nucleic Acid
- Tangier Disease -- genetics
- Transcriptome
- Young Adult
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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