Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease.

Zhang, Hanrui

Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease. [electronic resource] - Circulation research Jun 2015 - 17-28 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1524-4571

10.1161/CIRCRESAHA.117.305860 doi


ATP Binding Cassette Transporter 1--deficiency
Adult
Aged
Animals
Antigens, Differentiation--analysis
Base Sequence
Cell Culture Techniques
Cell Differentiation
Cells, Cultured
Cholesterol--metabolism
Embryoid Bodies--cytology
Female
Genotype
Humans
Induced Pluripotent Stem Cells--cytology
Inflammation
Interferon-gamma--pharmacology
Lipopolysaccharides--pharmacology
Macrophage Activation--drug effects
Macrophages--cytology
Male
Mice
Mice, Knockout
Molecular Sequence Data
Phagocytosis
Phenotype
RNA, Messenger--genetics
Sequence Alignment
Sequence Homology, Nucleic Acid
Tangier Disease--genetics
Transcriptome
Young Adult