PPARα inhibition modulates multiple reprogrammed metabolic pathways in kidney cancer and attenuates tumor growth. [electronic resource]
Producer: 20150804Description: C890-8 p. digitalISSN:- 1522-1563
- Animals
- Carcinoma, Renal Cell -- drug therapy
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Epithelial Cells -- drug effects
- Gene Expression Regulation, Neoplastic
- Humans
- Kidney Neoplasms -- drug therapy
- Kidney Tubules -- drug effects
- Metabolic Networks and Pathways -- drug effects
- Mice
- Mice, Nude
- Organ Specificity
- Oxazoles -- pharmacology
- PPAR alpha -- antagonists & inhibitors
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-myc -- antagonists & inhibitors
- RNA, Small Interfering -- genetics
- Signal Transduction
- Tyrosine -- analogs & derivatives
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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