MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition. [electronic resource]
Producer: 20160520Description: 8226-43 p. digitalISSN:- 1949-2553
- Breast Neoplasms -- metabolism
- Cell Line, Tumor
- Cellular Senescence
- Cyclin-Dependent Kinase 4 -- antagonists & inhibitors
- DNA Helicases -- biosynthesis
- Gene Knockdown Techniques
- Humans
- Liposarcoma
- Nuclear Proteins -- biosynthesis
- Phosphorylation
- Piperazines -- pharmacology
- Proto-Oncogene Proteins c-mdm2 -- metabolism
- Pyridines -- pharmacology
- Retinoblastoma Protein -- metabolism
- X-linked Nuclear Protein
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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