Alendronate inhalation ameliorates elastase-induced pulmonary emphysema in mice by induction of apoptosis of alveolar macrophages. [electronic resource]
Producer: 20160209Description: 6332 p. digitalISSN:- 2041-1723
- Administration, Inhalation
- Aerosols
- Alendronate -- pharmacology
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Antigens, Differentiation -- genetics
- Apoptosis -- drug effects
- Bone Density Conservation Agents -- pharmacology
- Bronchoalveolar Lavage Fluid -- chemistry
- CD11b Antigen -- genetics
- CD11c Antigen -- genetics
- Caspase 3 -- genetics
- Cell Movement -- drug effects
- Contrast Media -- metabolism
- Drug Repositioning
- Gene Expression
- Lung -- drug effects
- Macrophages, Alveolar -- drug effects
- Male
- Mevalonic Acid -- immunology
- Mice
- Mice, Inbred C57BL
- NF-kappa B -- genetics
- Pancreatic Elastase
- Phagocytosis -- drug effects
- Pulmonary Emphysema -- chemically induced
- Signal Transduction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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