Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-α/ASK1/JNK pathway. [electronic resource]
Producer: 20150709Description: H1143-54 p. digitalISSN:- 1522-1539
- Animals
- Apoptosis
- Cathepsin B -- antagonists & inhibitors
- Disease Models, Animal
- Female
- Fibrosis
- HEK293 Cells
- Humans
- Hypertrophy, Left Ventricular -- enzymology
- JNK Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- MAP Kinase Kinase Kinase 5 -- metabolism
- Male
- Mice, Knockout
- Myocytes, Cardiac -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- RNA Interference
- Signal Transduction
- Transfection
- Tumor Necrosis Factor-alpha -- metabolism
- Ventricular Function, Left -- drug effects
- Ventricular Remodeling -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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