Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis. [electronic resource]
Producer: 20151207Description: 969-86 p. digitalISSN:- 1525-2191
- Adult
- Alveolar Epithelial Cells -- drug effects
- Animals
- Apoptosis -- drug effects
- Cell Differentiation -- drug effects
- Cell Nucleus -- drug effects
- Cytoprotection -- drug effects
- Fibronectins -- metabolism
- Fibrosis
- Humans
- Inflammation -- pathology
- Lung -- metabolism
- Mesoderm -- drug effects
- Mice, Inbred C57BL
- Myofibroblasts -- pathology
- Nipecotic Acids -- administration & dosage
- Plasminogen Activator Inhibitor 1 -- metabolism
- Protein Transport -- drug effects
- Serum Response Factor -- metabolism
- Signal Transduction -- drug effects
- Sus scrofa
- Trans-Activators -- metabolism
- Transforming Growth Factor beta1 -- pharmacology
- X-Linked Inhibitor of Apoptosis Protein -- metabolism
- fas Receptor -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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