High doses of bisphosphonates reduce osteoblast-like cell proliferation by arresting the cell cycle and inducing apoptosis. [electronic resource]
Producer: 20160802Description: 396-401 p. digitalISSN:- 1878-4119
- Alendronate -- administration & dosage
- Apoptosis -- drug effects
- Bisphosphonate-Associated Osteonecrosis of the Jaw -- pathology
- Bone Density Conservation Agents -- administration & dosage
- Cell Cycle -- drug effects
- Cell Death -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Clodronic Acid -- administration & dosage
- Coloring Agents
- Diphosphonates -- administration & dosage
- Dose-Response Relationship, Drug
- Flow Cytometry -- methods
- G1 Phase -- drug effects
- Humans
- Ibandronic Acid
- Necrosis
- Osteoblasts -- drug effects
- Pamidronate
- Resting Phase, Cell Cycle -- drug effects
- Spectrophotometry -- methods
- Tetrazolium Salts
- Thiazoles
- Time Factors
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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