Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element. [electronic resource]
Producer: 20150420Description: 107-20 p. digitalISSN:- 1540-9538
- Animals
- CCCTC-Binding Factor
- Cell Lineage -- genetics
- Cells, Cultured
- Chromatin -- genetics
- Enhancer Elements, Genetic -- genetics
- Gene Expression Regulation
- Histones -- metabolism
- In Situ Hybridization, Fluorescence -- methods
- Methylation
- Mice, Inbred C57BL
- Mice, Knockout
- Precursor Cells, B-Lymphoid -- cytology
- Promoter Regions, Genetic -- genetics
- Protein Binding
- Receptors, Antigen, T-Cell, alpha-beta -- genetics
- Repressor Proteins -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Thymocytes -- cytology
- V(D)J Recombination -- genetics
- VDJ Recombinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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