Suppression of NF-κB signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone. [electronic resource]
Producer: 20170904Description: 146-56 p. digitalISSN:- 1096-0333
- Animals
- Benzofurans -- pharmacology
- Cell Line
- Colitis -- chemically induced
- Dextran Sulfate -- toxicity
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Humans
- Inflammasomes -- antagonists & inhibitors
- Macrophages, Peritoneal -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- NF-kappa B -- antagonists & inhibitors
- NLR Family, Pyrin Domain-Containing 3 Protein -- antagonists & inhibitors
- Signal Transduction -- drug effects
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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